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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Transneuronal degeneration ： ウィキペディア英語版 Transneuronal degeneration Transneuronal degeneration is the death of neurons resulting from the disruption of input from or output to other nearby neurons.〔http://medical-dictionary.thefreedictionary.com/transneuronal+degeneration〕 It is an active excitotoxic process when a neuron is overstimulated by a neurotransmitter (most commonly glutamate)〔http://medical-dictionary.thefreedictionary.com/Excitotoxicity〕 causing the dysfunction of that neuron (either damaging it or killing it) which drives neighboring neurons into metabolic deficit, resulting in rapid, widespread loss of neurons. This can be either anterograde or retrograde, indicating the direction of the degeneration relative to the original site of damage (see types). There are varying causes for transneuronal degeneration such as brain lesions, disconnection syndromes, respiratory chain deficient neuron interaction, and lobectomies. Although there are different causes, transneuronal degeneration generally results in the same effects (whether they be cellular, dendritic, or axonal) to varying degrees. Transneuronal degeneration is thought to be linked to a number of diseases, most notably Huntington's disease and Alzheimer's disease, and researchers recently have been performing experiments with monkeys and rats, monitoring lesions in different parts of the body to study more closely how exactly the process works. ==Types== Transneuronal degeneration can be grouped into two general categories: anterograde and retrograde. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Transneuronal degeneration」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.